ImmunityBio, Inc. is a late-stage immunotherapy company developing a broad pipeline of next-generation therapies that drive immunogenic mechanisms for defeating cancer and infectious disease. The company's immunotherapy platform is designed to activate both the innate (natural killer cell and macrophage) and adaptive (T cell) immune systems to create long-term "immunological memory." The U.S. Food and Drug Administration (FDA) has accepted for review ImmunityBio's resubmission of its Biologics License Application (BLA) for N-803, a first-in-class IL-15 superagonist, plus Bacillus Calmette-Guerin (BCG) for the treatment of BCG-unresponsive non-muscle-invasive bladder cancer carcinoma in situ (CIS) with or without Ta or T1 disease, and has set a user fee goal date (PDUFA date) of April 23, 2024.

Why ImmunityBio?

* ImmunityBio is developing cutting edge technology with the goal to transform the lives of patients with cancer and develop next-generation therapies and vaccines that complement, harness and amplify the immune system to defeat cancers and infectious diseases.

* Opportunity to join an early-stage public biopharmaceutical company with a headquarters in Southern California.

* Work with a collaborative team with the ability to work across different areas at the company.

* Ability to join a growing company with development opportunities.

Position Summary

The Microfluidics Engineer III serves as a key member of the device engineering team to develop a microfluidic-based platform and workflow for mammalian cell processing. This position will act as lead on the microfluidics platform; design and fabricate microfluidic devices; and perform experiments to evaluate and iterate the device design systematically. The role will have significant freedom on the platform design, with accountability to, and support from, the engineering team developing other aspects of: instruments, consumables, and reagents for the system. The role will also work closely with scientists in the biologics R&D team to evaluate and optimize the device platform for the intended applications in manufacturing cellular therapeutics.

Essential Functions

• Design and manufacture plastic/polymer microfluidic devices for testing and use design-for-manufacturing best practices to transition to production, assembly, and packaging.
• Design and conduct experiments to evaluate device performance and iterate device design through literature studies, fundamental multiphysics modeling, and empirical testing.
• Assist in defining system specifications and requirements and work with the rest of the engineering team to implement the system
• Perform other routine job duties as needed.

Education & Experience

• Masters of Science degree with 2-5 years of experience; or Ph.D. in related engineering or applied scientific fields such as bioengineering, mechanical engineering, electrical engineering.
• Experience in biomedical microfluidic system prototyping and development
• MEMS/BioMEMS cleanroom microfabrication experience required
• PDMS-based microfluidic device prototyping experience required
• 2D/3D CAD modeling, multiphysics simulation tools (e.g. COMSOL) preferred

Knowledge, Skills, & Abilities

• Thorough knowledge of the mechanics and fluid dynamics governing microfluidic systems required
• Basic knowledge of biology and cell culture / cell handling experience preferred
• Due to the independent nature of the position, it is a vital to have the ability to clearly document and communicate successes and struggles through regular verbal discussions, writing, and group presentations
• Problem-solving and critical thinking skills are a necessity

Working Environment / Physical Environment

• This role will work predominately on-site at Culver City and occasionally at UCLA's NanoLab
• Hybrid remote work is acceptable on an ad-hoc basis after discussion with the manager
• The working environment is within an approximately 2,000 square foot lab space equipped with biosafety cabinets for mammalian cell culture and equipment to complete the tasks described above.
• Occasionally: Transporting small equipment required

This position is eligible for a discretionary bonus and equity award. The annual base pay range for this position is below. The specific rate will depend on the successful candidate's qualifications, prior experience as well as geographic location.

$115,000 (entry-level qualifications) to $140,000 (highly experienced)

The application window is anticipated to close on 60 days from when it is posted or sooner if the position is filled or closed.

ImmunityBio employees are as valuable as the people we serve. We have built a resource of robust benefit offerings to best support the total wellbeing of our team members and their families. Our competitive total rewards benefits package, for eligible employees, include: Medical, Dental and Vision Plan Options * Health and Financial Wellness Programs * Employer Assistance Program (EAP) * Company Paid and Voluntary Life/AD&D, Short-Term and Long-Term Disability * Healthcare and Dependent Care Flexible Spending Accounts * 401(k) Retirement Plan with Company Match * 529 Education Savings Program * Voluntary Legal Services, Identity Theft Protection, Pet Insurance and Employee Discounts, Rewards and Perks * Paid Time Off (PTO) includes: 11 Holidays * Exempt Employees are eligible for Unlimited PTO * Non-Exempt Employees are eligible for 10 Vacation Days, 56 Hours of Health Pay, 2 Personal Days and 1 Cultural Day * We are committed to providing you with the tools and resources you need to optimize your Health and Wellness.

At ImmunityBio, we are an equal opportunity employer dedicated to diversity in the workplace. Our policy is to provide equal employment opportunities to all qualified persons without regard to race, gender, color, disability, national origin, age, religion, union affiliation, sexual orientation, veteran status, citizenship, gender identity and/or expression, or other status protected by law.

ImmunityBio is a mandatory vaccination employer for COVID-19 and its variants. The Company requires that its employees be fully vaccinated as of their start date. If you require a medical or religious accommodation we will engage in the interactive process with you. Proof of vaccination will be required prior to start. If we make you an offer and you are not yet vaccinated, we will accommodate a delay in start date. ImmunityBio may also mandate that its employees receive vaccine boosters, and all accommodation laws will be followed.