The Quigley lab is a primarily computational group that studies how tumors develop resistance to cancer therapies. We are seeking a staff bioinformatician for projects that define how resistance to targeted therapy arises, and how genomic and epigenomic alterations determine which patients will benefit from a therapy. Recent projects from our group have been published in Cell, Nature Genetics, and Cancer Discovery (see https://quigleylab.ucsf.edu). The candidate will work in a collaborative environment to develop one or more projects using a combination of DNA, transcriptome, and epigenomics assays. Most of our data are unpublished. Current projects include single nucleus RNA & ATAC-seq analysis, perturb-seq, and spatial transcriptomics.

Required qualifications

• Assistant Specialist- Master's degree or a baccalaureate degree with 3 or more years of research experience.
• Associate Specialist- Master's degree (or equivalent degree) or five to ten years of experience in the relevant specialization
• Full Specialist- Terminal degree (or equivalent degree) or ten or more years of experience in the relevant specialization

Basic Skills required

• At least three years of experience programming with R or Python.
• Willingness and ability to learn new methods and skills for changing research priorities.
• Excellent organizational and interpersonal communication skills (verbal and written)

Preferred qualifications

• Strong command of using Unix
• Probability & statistics for data analysis, particularly linear models and permutation
• Prior experience analyzing DNA variation and RNA-seq. Experience combining transcriptomic and epigenomic analysis (one or more of ATAC-seq, ChIP-seq, or methylation data) is highly desirable.
• Familiarity with molecular biology & cancer genetics concepts
• Analysis of single cell transcriptomic data
• Experience applying machine learning methods to interpret biological data
• Prior experience applying bioinformatics to problems in cancer biology

Please apply online at https://aprecruit.ucsf.edu/JPF05053, with a CV, cover letter, and three references.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $59,200-$181,800.

• 3 required (contact information only)

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.