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Scientist
Irvine, CA
Job Description
Job Title: Scientist
Location: South San Francisco, CA
Duration: 6 months
What are the top 3-5 skills, experience or education required for this position?
BS in Biological Sciences or Chemical/Biochemical Engineering or related field with typically 0-3 years of industry experience; or, MS with no additional experience 1. Time management 2. Adaptable ability 3. Communication 4. Familiarity with solution prep 5. Some exp. with aseptic technique (can be from course)
Daily Work Schedule Expectations
Monday to Friday with infrequent weekend work maybe 3 or 4 times during assignment when fully trained. Will be able to take a weekday off when this happens
Responsibilities
* Perform routine tasks such as media/buffer preparation, thawing of cryopreserved cells, cell culture passaging, aseptic sampling and banking competently and independently to support ongoing projects in cell culture lab
* Take routine analytical measurements for cell growth, gas-content analysis, pH, osmolality, nutrient and metabolite measurements and HPLC analysis of monoclonal antibody titers
* Utilize technical expertise and available information to troubleshoot and resolve operational hurdles when encountered and adapt protocols as necessary
* Collaborate across CMC functions to optimize bioprocess parameters for the production of difficult-to-manufacture biologics
* Execute high-throughput fed batch and batch experiments and perform data analysis of the same
* Able to maintain a "can-do" attitude to complete innovative projects while being flexible in work priorities based on business needs
* Perform tasks with rigorous attention to detail consistently. Prioritize tasks and contribute to a highly motivated and productive team with a sense of urgency and desire to meet project timelines
* Accurately document, critically analyze/interpret data and communicate the results promptly through various electronic means
* Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials
* Must be comfortable with physical activities of constant standing, walking, and sitting with arm stretching into biosafety cabinets for cell culture work and occasionally lifting 50Ibs.
* Strong interpersonal skills to thrive in a team environment
Experience Qualifications
* BS in Biological Sciences or Chemical/Biochemical Engineering or related field with typically 0-3 years of industry experience; or, MS with no additional experience
* Prior experience in bioreactor operation and cell culture media preparation is a must
* Industry experience in sterile fermentation techniques preferably mammalian cell culture
* Experience in single use mammalian cell culture tools employed in bioprocess development, including but not limited to deep well plates, shake flasks, ambr250s, stirred tank reactors
* Excellent aseptic techniques and familiarity with principles of sterilization/disinfection.
* Familiar with general troubleshooting techniques and implementation of quality controls in developmental lab
* Experience with process development, optimization, and troubleshooting
* Experience in setting up high throughput experiments in both fed batch and batch modes, and comfortable with automation and manual operation when needed.
* Comfortable with practical considerations needed to successfully scale up conditions tested in high throughput systems to larger scales
* Excellent communication skills and experience using collaborative cloud-based technologies to in a hybrid working environment.
* Basic knowledge on biological data collection and analysis tools (GraphPad Prism, HPLCs, Blood gas analyzers, metabolite analyzers) and computer applications such as MS Word, MS Excel and MS PowerPoint.
* Able to maintain instrumentation, inventory and cleanliness of a developmental lab to create a safe, effective and efficient scientific working environment.
* Familiarity with the use of single use mammalian cell culture technologies such as deep well plates, shake flasks, ambr250s, stirred tank bioreactors
Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances. Additional benefits SPECTRAFORCE offers to the eligible employees include commuter benefits, 401K plan with matching and a referral bonus program. SPECTRAFORCE offers unpaid leave as well as paid sick leave when required by law.
SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at nahr@spectraforce.com if you require reasonable accommodation.
Location: South San Francisco, CA
Duration: 6 months
What are the top 3-5 skills, experience or education required for this position?
BS in Biological Sciences or Chemical/Biochemical Engineering or related field with typically 0-3 years of industry experience; or, MS with no additional experience 1. Time management 2. Adaptable ability 3. Communication 4. Familiarity with solution prep 5. Some exp. with aseptic technique (can be from course)
Daily Work Schedule Expectations
Monday to Friday with infrequent weekend work maybe 3 or 4 times during assignment when fully trained. Will be able to take a weekday off when this happens
Responsibilities
* Perform routine tasks such as media/buffer preparation, thawing of cryopreserved cells, cell culture passaging, aseptic sampling and banking competently and independently to support ongoing projects in cell culture lab
* Take routine analytical measurements for cell growth, gas-content analysis, pH, osmolality, nutrient and metabolite measurements and HPLC analysis of monoclonal antibody titers
* Utilize technical expertise and available information to troubleshoot and resolve operational hurdles when encountered and adapt protocols as necessary
* Collaborate across CMC functions to optimize bioprocess parameters for the production of difficult-to-manufacture biologics
* Execute high-throughput fed batch and batch experiments and perform data analysis of the same
* Able to maintain a "can-do" attitude to complete innovative projects while being flexible in work priorities based on business needs
* Perform tasks with rigorous attention to detail consistently. Prioritize tasks and contribute to a highly motivated and productive team with a sense of urgency and desire to meet project timelines
* Accurately document, critically analyze/interpret data and communicate the results promptly through various electronic means
* Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials
* Must be comfortable with physical activities of constant standing, walking, and sitting with arm stretching into biosafety cabinets for cell culture work and occasionally lifting 50Ibs.
* Strong interpersonal skills to thrive in a team environment
Experience Qualifications
* BS in Biological Sciences or Chemical/Biochemical Engineering or related field with typically 0-3 years of industry experience; or, MS with no additional experience
* Prior experience in bioreactor operation and cell culture media preparation is a must
* Industry experience in sterile fermentation techniques preferably mammalian cell culture
* Experience in single use mammalian cell culture tools employed in bioprocess development, including but not limited to deep well plates, shake flasks, ambr250s, stirred tank reactors
* Excellent aseptic techniques and familiarity with principles of sterilization/disinfection.
* Familiar with general troubleshooting techniques and implementation of quality controls in developmental lab
* Experience with process development, optimization, and troubleshooting
* Experience in setting up high throughput experiments in both fed batch and batch modes, and comfortable with automation and manual operation when needed.
* Comfortable with practical considerations needed to successfully scale up conditions tested in high throughput systems to larger scales
* Excellent communication skills and experience using collaborative cloud-based technologies to in a hybrid working environment.
* Basic knowledge on biological data collection and analysis tools (GraphPad Prism, HPLCs, Blood gas analyzers, metabolite analyzers) and computer applications such as MS Word, MS Excel and MS PowerPoint.
* Able to maintain instrumentation, inventory and cleanliness of a developmental lab to create a safe, effective and efficient scientific working environment.
* Familiarity with the use of single use mammalian cell culture technologies such as deep well plates, shake flasks, ambr250s, stirred tank bioreactors
Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances. Additional benefits SPECTRAFORCE offers to the eligible employees include commuter benefits, 401K plan with matching and a referral bonus program. SPECTRAFORCE offers unpaid leave as well as paid sick leave when required by law.
Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at if you require reasonable accommodation.
CPRA: The Company is committed to complying with the California Privacy Rights Act ("CPRA") effective January 1, 2023; and all data privacy laws in the jurisdictions in which it recruits and hires employees. A Notice to California Job Applicants Regarding the Collection of Personal Information can be located on our website. Applicants with disabilities may access this notice in an alternative format by contacting .
SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at nahr@spectraforce.com if you require reasonable accommodation.
Job Summary
Company
Start Date
As soon as possible
Employment Term and Type
Regular, Full Time
Required Education
Bachelor's Degree
Required Experience
0 to 3 years
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